Condensation of Ded1p Promotes a Translational Switch from Housekeeping to Stress Protein Production

Cells sense elevated temperatures and mount an adaptive heat shock response that involves changes in gene expression, but the underlying mechanisms, particularly on the level of translation, remain unknown. Here we report that, in budding yeast, the essential translation initiation factor Ded1p unde...

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Detalles Bibliográficos
Autores principales: Iserman, Christiane, Desroches Altamirano, Christine, Jegers, Ceciel, Friedrich, Ulrike, Zarin, Taraneh, Fritsch, Anatol W., Mittasch, Matthäus, Domingues, Antonio, Hersemann, Lena, Jahnel, Marcus, Richter, Doris, Guenther, Ulf-Peter, Hentze, Matthias W., Moses, Alan M., Hyman, Anthony A., Kramer, Günter, Kreysing, Moritz, Franzmann, Titus M., Alberti, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237889/
https://www.ncbi.nlm.nih.gov/pubmed/32359423
http://dx.doi.org/10.1016/j.cell.2020.04.009

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