Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals

Understanding adaptive immunity to SARS-CoV-2 is important for vaccine development, interpreting coronavirus disease 2019 (COVID-19) pathogenesis, and calibration of pandemic control measures. Using HLA class I and II predicted peptide “megapools,” circulating SARS-CoV-2-specific CD8(+) and CD4(+) T...

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Detalles Bibliográficos
Autores principales: Grifoni, Alba, Weiskopf, Daniela, Ramirez, Sydney I., Mateus, Jose, Dan, Jennifer M., Moderbacher, Carolyn Rydyznski, Rawlings, Stephen A., Sutherland, Aaron, Premkumar, Lakshmanane, Jadi, Ramesh S., Marrama, Daniel, de Silva, Aravinda M., Frazier, April, Carlin, Aaron F., Greenbaum, Jason A., Peters, Bjoern, Krammer, Florian, Smith, Davey M., Crotty, Shane, Sette, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237901/
https://www.ncbi.nlm.nih.gov/pubmed/32473127
http://dx.doi.org/10.1016/j.cell.2020.05.015

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