Cargando…

β-Sitosterol Loaded Nanostructured Lipid Carrier: Physical and Oxidative Stability, In Vitro Simulated Digestion and Hypocholesterolemic Activity

The objective of the present study was to explore the potential of nanostructured lipid carriers (NLCs) for improving the oral delivery of β-sitosterol, a poorly water-soluble bioactive component with hypocholesterolemic activity. Two β-sitosterol formulations with different solid lipid compositions...

Descripción completa

Detalles Bibliográficos
Autores principales:	Soleimanian, Yasamin, Goli, Sayed Amir Hossein, Varshosaz, Jaleh, Di Cesare Mannelli, Lorenzo, Ghelardini, Carla, Cirri, Marzia, Maestrelli, Francesca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237988/ https://www.ncbi.nlm.nih.gov/pubmed/32331384 http://dx.doi.org/10.3390/pharmaceutics12040386

Ejemplares similares

Combined Approach of Cyclodextrin Complexationand Nanostructured Lipid Carriers for the Development of a Pediatric Liquid Oral Dosage Form of Hydrochlorothiazide
por: Cirri, Marzia, et al.
Publicado: (2018)

Design, characterization and in vivo evaluation of nanostructured lipid carriers (NLC) as a new drug delivery system for hydrochlorothiazide oral administration in pediatric therapy
por: Cirri, Marzia, et al.
Publicado: (2018)

Improvement of Butamben Anesthetic Efficacy by the Development of Deformable Liposomes Bearing the Drug as Cyclodextrin Complex
por: Mura, Paola, et al.
Publicado: (2021)

Evaluation and Comparison of Solid Lipid Nanoparticles (SLNs) and Nanostructured Lipid Carriers (NLCs) as Vectors to Develop Hydrochlorothiazide Effective and Safe Pediatric Oral Liquid Formulations
por: Mura, Paola, et al.
Publicado: (2021)

Design, Evaluation and Comparison of Nanostructured Lipid Carriers and Chitosan Nanoparticles as Carriers of Poorly Soluble Drugs to Develop Oral Liquid Formulations Suitable for Pediatric Use
por: Nerli, Giulia, et al.
Publicado: (2023)

Optimization of LDL targeted nanostructured lipid carriers of 5-FU by a full factorial design
por: Andalib, Sare, et al.
Publicado: (2012)

Brain delivery of valproic acid via intranasal administration of nanostructured lipid carriers: in vivo pharmacodynamic studies using rat electroshock model
por: Eskandari, Sharareh, et al.
Publicado: (2011)

Fabrication and Evaluation of Spironolactone-Loaded Nanostructured Lipid Carries for Cardiac Tissue Regeneration
por: Falak, Mehrzad, et al.
Publicado: (2020)

Multiple Roles of Chitosan in Mucosal Drug Delivery: An Updated Review
por: Mura, Paola, et al.
Publicado: (2022)

Microneedle mediated transdermal delivery of β-sitosterol loaded nanostructured lipid nanoparticles for androgenic alopecia
por: Prabahar, Kousalya, et al.
Publicado: (2022)

Polysaccharide Structures and Their Hypocholesterolemic Potential
por: Silva, Inês M. V., et al.
Publicado: (2021)

Development and Characterization of Cyclodextrin-Based Nanogels as a New Ibuprofen Cutaneous Delivery System
por: Cirri, Marzia, et al.
Publicado: (2022)

Role of Cyclodextrins and Drug Solid State Properties on Flufenamic Acid Dissolution Performance from Tablets
por: Maestrelli, Francesca, et al.
Publicado: (2022)

In Vitro Hypocholesterolemic Effect of Coffee Compounds
por: Coreta-Gomes, Filipe Manuel, et al.
Publicado: (2020)

Preparation and characterization of celecoxib solid dispersions; comparison of poloxamer-188 and PVP-K30 as carriers
por: Homayouni, Alireza, et al.
Publicado: (2014)

Formulation development and evaluation of metformin chewing gum with bitter taste masking
por: Mostafavi, Sayed Abolfazl, et al.
Publicado: (2014)

5FU-loaded PCL/Chitosan/Fe(3)O(4) Core-Shell Nanofibers Structure: An Approach to Multi-Mode Anticancer System
por: Hadjianfar, Mehdi, et al.
Publicado: (2022)

Tablets of “Hydrochlorothiazide in Cyclodextrin in Nanoclay”: A New Nanohybrid System with Enhanced Dissolution Properties
por: Maestrelli, Francesca, et al.
Publicado: (2020)

Hypocholesterolemic effect of Terminalia chebula fruit (Myrobalan) in mice
por: Rathore, H.S., et al.
Publicado: (2004)

POSSIBLE HYPOCHOLESTEROLEMIC EFFECT OF GINGER AND ROSEMARY OILS IN RATS
por: Eissa, Fatma A., et al.
Publicado: (2017)

Stability and antimicrobial effect of amikacin-loaded solid lipid nanoparticles
por: Ghaffari, Solmaz, et al.
Publicado: (2011)

Formulation and Characterization of Quercetin-loaded Oil in Water Nanoemulsion and Evaluation of Hypocholesterolemic Activity in Rats
por: Son, Hye-Yeon, et al.
Publicado: (2019)

Development of a Cyclodextrin-Based Mucoadhesive-Thermosensitive In Situ Gel for Clonazepam Intranasal Delivery
por: Cirri, Marzia, et al.
Publicado: (2021)

Combined Use of Cyclodextrins and Amino Acids for the Development of Cefixime Oral Solutions for Pediatric Use
por: Cirri, Marzia, et al.
Publicado: (2021)

Effect of different types of surfactants on the physical properties and stability of carvedilol nano-niosomes
por: Taymouri, Somayeh, et al.
Publicado: (2016)

Solubility Enhancement of Domperidone by Solvent Change In situ Micronization Technique
por: Enteshari, Saeede, et al.
Publicado: (2018)

Experimental Studies on the Hypocholesterolemic Effect of Commiphora Mukul. Engl. (GUGGUL)
por: Satyavati, G. V., et al.
Publicado: (2013)

Hypocholesterolemic efficacy of royal jelly in healthy mild hypercholesterolemic adults
por: Chiu, Hui-Fang, et al.
Publicado: (2016)

Hypocholesterolemic Effects of Probiotic Mixture on Diet-Induced Hypercholesterolemic Rats
por: Kim, Shang-Jin, et al.
Publicado: (2017)

Gut microbiome responses to dietary intervention with hypocholesterolemic vegetable oils
por: Lim, Rachel Rui Xia, et al.
Publicado: (2022)

Effect of β-sitosterol self-microemulsion and β-sitosterol ester with linoleic acid on lipid-lowering in hyperlipidemic mice
por: Yuan, Chuanxun, et al.
Publicado: (2019)

Anti-Hepatocellular-Cancer Activity Exerted by β-Sitosterol and β-Sitosterol-Glucoside from Indigofera zollingeriana Miq
por: Vo, Tuong Kha, et al.
Publicado: (2020)

Development of dry powder inhaler containing tadalafil-loaded PLGA nanoparticles
por: Varshosaz, Jaleh, et al.
Publicado: (2017)

Preparation, Optimization, and Screening of the Effect of Processing Variables on Agar Nanospheres Loaded with Bupropion HCl by a D-Optimal Design
por: Varshosaz, Jaleh, et al.
Publicado: (2015)

Nanostructured Lipid Carriers Loaded with Baicalin: An Efficient Carrier for Enhanced Antidiabetic Effects
por: Shi, Feng, et al.
Publicado: (2016)

Improvement of fluvastatin bioavailability by loading on nanostructured lipid carriers
por: El-Helw, Abdel-Rahim M, et al.
Publicado: (2015)

Why Do Plants Convert Sitosterol to Stigmasterol?
por: Aboobucker, Siddique I., et al.
Publicado: (2019)

Improving the solubility and in vitro cytotoxicity (anticancer activity) of ferulic acid by loading it into cyclodextrin nanosponges
por: Rezaei, Atefe, et al.
Publicado: (2019)

Lipid Nanocapsule-Based Gels for Enhancement of Transdermal Delivery of Ketorolac Tromethamine
por: Varshosaz, Jaleh, et al.
Publicado: (2011)

Optimization of Poly(methyl vinyl ether-co-maleic acid) Electrospun Nanofibers as a Fast-Dissolving Drug Delivery System
por: Varshosaz, Jaleh, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_ir3ksc3l5cbsv5851091r33vfv