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Characterization and Mathematical Modeling of Alginate/Chitosan-Based Nanoparticles Releasing the Chemokine CXCL12 to Attract Glioblastoma Cells

Chitosan (Chit) currently used to prepare nanoparticles (NPs) for brain application can be complexed with negatively charged polymers such as alginate (Alg) to better entrap positively charged molecules such as CXCL12. A sustained CXCL12 gradient created by a delivery system can be used, as a therap...

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Detalles Bibliográficos
Autores principales: Gascon, Suzanne, Giraldo Solano, Angéla, El Kheir, Wiam, Therriault, Hélène, Berthelin, Pierre, Cattier, Bettina, Marcos, Bernard, Virgilio, Nick, Paquette, Benoit, Faucheux, Nathalie, Lauzon, Marc-Antoine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238026/
https://www.ncbi.nlm.nih.gov/pubmed/32295255
http://dx.doi.org/10.3390/pharmaceutics12040356

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