An Interspecies Molecular and Functional Study of Organic Cation Transporters at the Blood-Brain Barrier: From Rodents to Humans

Organic cation transporters (OCTs) participate in the handling of compounds in kidneys and at the synaptic cleft. Their role at the blood-brain barrier (BBB) in brain drug delivery is still unclear. The presence of OCT1,2,3 (SLC22A1-3) in mouse, rat and human isolated brain microvessels was investig...

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Detalles Bibliográficos
Autores principales: Chaves, Catarina, Campanelli, Federica, Chapy, Hélène, Gomez-Zepeda, David, Glacial, Fabienne, Smirnova, Maria, Taghi, Meryam, Pallud, Johan, Perrière, Nicolas, Declèves, Xavier, Menet, Marie-Claude, Cisternino, Salvatore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238036/
https://www.ncbi.nlm.nih.gov/pubmed/32231079
http://dx.doi.org/10.3390/pharmaceutics12040308

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