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Interaction of Lipoplex with Albumin Enhances Gene Expression in Hepatitis Mice

Understanding the in vivo fate of lipoplex, which is composed of cationic liposomes and DNA, is an important issue toward gene therapy. In disease conditions, the fate of lipoplex might change compared with the normal condition. Here, we examined the contribution of interaction with serum components...

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Detalles Bibliográficos
Autores principales: Yoshikawa, Naoki, Fumoto, Shintaro, Yoshikawa, Keiko, Hu, Die, Okami, Kazuya, Kato, Riku, Nakashima, Mikiro, Miyamoto, Hirotaka, Nishida, Koyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238045/
https://www.ncbi.nlm.nih.gov/pubmed/32290201
http://dx.doi.org/10.3390/pharmaceutics12040341