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Quality by Design Optimization of Cold Sonochemical Synthesis of Zidovudine-Lamivudine Nanosuspensions

Lamivudine (3TC) and zidovudine (AZT) are antiviral agents used to manage HIV/AIDS infection. The compounds require frequent dosing, exhibit unpredictable bioavailability and a side effect profile that includes hepato- and haema-toxicity. A novel pseudo one-solvent bottom-up approach and Design of E...

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Detalles Bibliográficos
Autores principales:	Witika, Bwalya A., Smith, Vincent J., Walker, Roderick B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238087/ https://www.ncbi.nlm.nih.gov/pubmed/32316398 http://dx.doi.org/10.3390/pharmaceutics12040367

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