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Strong and Selective Inhibitory Effects of the Biflavonoid Selamariscina A against CYP2C8 and CYP2C9 Enzyme Activities in Human Liver Microsomes

Like flavonoids, biflavonoids, dimeric flavonoids, and polyphenolic plant secondary metabolites have antioxidant, antibacterial, antiviral, anti-inflammatory, and anti-cancer properties. However, there is limited data on their effects on cytochrome P450 (P450) and uridine 5′-diphosphoglucuronosyl tr...

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Detalles Bibliográficos
Autores principales: Park, So-Young, Nguyen, Phi-Hung, Kim, Gahyun, Jang, Su-Nyeong, Lee, Ga-Hyun, Phuc, Nguyen Minh, Wu, Zhexue, Liu, Kwang-Hyeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238120/
https://www.ncbi.nlm.nih.gov/pubmed/32290339
http://dx.doi.org/10.3390/pharmaceutics12040343