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Controlled Release of rAAV Vectors from APMA-Functionalized Contact Lenses for Corneal Gene Therapy

As an alternative to eye drops and ocular injections for gene therapy, the aim of this work was to design for the first time hydrogel contact lenses that can act as platforms for the controlled delivery of viral vectors (recombinant adeno-associated virus, rAAV) to the eye in an effective way with i...

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Detalles Bibliográficos
Autores principales: Alvarez-Rivera, Fernando, Rey-Rico, Ana, Venkatesan, Jagadeesh K, Diaz-Gomez, Luis, Cucchiarini, Magali, Concheiro, Angel, Alvarez-Lorenzo, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238179/
https://www.ncbi.nlm.nih.gov/pubmed/32283694
http://dx.doi.org/10.3390/pharmaceutics12040335

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