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Dual Angiotensin Receptor and Neprilysin Inhibitor Ameliorates Portal Hypertension in Portal Hypertensive Rats

Background: Portal hypertension is characterized by exaggerated activation of the renin-angiotensin-aldosterone axis. Natriuretic peptide system plays a counter-regulatory role, which is modulated by neprilysin. LCZ696 (sacubitril/valsartan) is a dual angiotensin receptor and neprilysin inhibitor. T...

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Detalles Bibliográficos
Autores principales:	Hsu, Shao-Jung, Huang, Hui-Chun, Chuang, Chiao-Lin, Chang, Ching-Chih, Hou, Ming-Chih, Lee, Fa-Yauh, Lee, Shou-Dong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238216/ https://www.ncbi.nlm.nih.gov/pubmed/32252377 http://dx.doi.org/10.3390/pharmaceutics12040320

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