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Obesity: novel and unusual predisposing factors

To tackle the complexity of the global obesity epidemic, it is important to consider the many predisposing factors that underlie progressive and sustained weight gain. Some of the biological drivers for weight gain following initial weight loss include persistent changes in appetite hormones [includ...

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Autores principales: Hanson, Petra, Weickert, Martin O., Barber, Thomas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238298/
https://www.ncbi.nlm.nih.gov/pubmed/32489583
http://dx.doi.org/10.1177/2042018820922018
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author Hanson, Petra
Weickert, Martin O.
Barber, Thomas M.
author_facet Hanson, Petra
Weickert, Martin O.
Barber, Thomas M.
author_sort Hanson, Petra
collection PubMed
description To tackle the complexity of the global obesity epidemic, it is important to consider the many predisposing factors that underlie progressive and sustained weight gain. Some of the biological drivers for weight gain following initial weight loss include persistent changes in appetite hormones [including ghrelin and postprandial plasma peptide YY (PYY)], and ‘persistent metabolic adaptation’. However, many factors within our busy, stressful modern-day environment seem to conspire towards promotion of weight gain. These include the effects of sleep deprivation on appetite regulation, and the effects of modern-day technology on ‘attention competition’. These factors, combined with cultural and societal factors can result in a ‘mindless’ attitude regarding eating-related behaviour that is likely to predispose to weight gain. In addition to the external environment, our internal environment within the gut has also changed radically within the last few decades, resulting from changes in fibre intake, and increased ingestion of highly refined, sterilised and processed foods. Although contentious, these dietary changes have implications for our gut microbiota, and possible downstream effects on control of appetite and metabolism. In this brief review, we consider some of the novel predisposing factors for weight gain within our modern-day 21st century environments (both external and internal), and explore how legal terminology can help to conceptualise the numerous factors that contribute towards weight gain, and, ultimately the global obesity epidemic.
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spelling pubmed-72382982020-06-01 Obesity: novel and unusual predisposing factors Hanson, Petra Weickert, Martin O. Barber, Thomas M. Ther Adv Endocrinol Metab Review To tackle the complexity of the global obesity epidemic, it is important to consider the many predisposing factors that underlie progressive and sustained weight gain. Some of the biological drivers for weight gain following initial weight loss include persistent changes in appetite hormones [including ghrelin and postprandial plasma peptide YY (PYY)], and ‘persistent metabolic adaptation’. However, many factors within our busy, stressful modern-day environment seem to conspire towards promotion of weight gain. These include the effects of sleep deprivation on appetite regulation, and the effects of modern-day technology on ‘attention competition’. These factors, combined with cultural and societal factors can result in a ‘mindless’ attitude regarding eating-related behaviour that is likely to predispose to weight gain. In addition to the external environment, our internal environment within the gut has also changed radically within the last few decades, resulting from changes in fibre intake, and increased ingestion of highly refined, sterilised and processed foods. Although contentious, these dietary changes have implications for our gut microbiota, and possible downstream effects on control of appetite and metabolism. In this brief review, we consider some of the novel predisposing factors for weight gain within our modern-day 21st century environments (both external and internal), and explore how legal terminology can help to conceptualise the numerous factors that contribute towards weight gain, and, ultimately the global obesity epidemic. SAGE Publications 2020-05-19 /pmc/articles/PMC7238298/ /pubmed/32489583 http://dx.doi.org/10.1177/2042018820922018 Text en © The Author(s), 2020 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Review
Hanson, Petra
Weickert, Martin O.
Barber, Thomas M.
Obesity: novel and unusual predisposing factors
title Obesity: novel and unusual predisposing factors
title_full Obesity: novel and unusual predisposing factors
title_fullStr Obesity: novel and unusual predisposing factors
title_full_unstemmed Obesity: novel and unusual predisposing factors
title_short Obesity: novel and unusual predisposing factors
title_sort obesity: novel and unusual predisposing factors
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238298/
https://www.ncbi.nlm.nih.gov/pubmed/32489583
http://dx.doi.org/10.1177/2042018820922018
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