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Radiation-Induced Left Main Coronary Artery Stenosis in a Patient with Atretic Internal Mammary Arteries

Coronary artery disease (CAD) is a known potential complication of thoracic radiation treatment that typically affects the proximal segments of the coronary arteries, requiring coronary artery bypass grafting (CABG). We present a case of acute coronary syndrome occurring in a 57-year-old man with pr...

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Autores principales: Dogra, Siddhant, Mahajan, Asha M., Jung, Albert, Attubato, Michael, Saric, Muhamed, Shah, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238366/
https://www.ncbi.nlm.nih.gov/pubmed/32455030
http://dx.doi.org/10.1155/2020/7970305
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author Dogra, Siddhant
Mahajan, Asha M.
Jung, Albert
Attubato, Michael
Saric, Muhamed
Shah, Alan
author_facet Dogra, Siddhant
Mahajan, Asha M.
Jung, Albert
Attubato, Michael
Saric, Muhamed
Shah, Alan
author_sort Dogra, Siddhant
collection PubMed
description Coronary artery disease (CAD) is a known potential complication of thoracic radiation treatment that typically affects the proximal segments of the coronary arteries, requiring coronary artery bypass grafting (CABG). We present a case of acute coronary syndrome occurring in a 57-year-old man with prior thoracic radiation therapy following resection of a chest wall chondrosarcoma. Coronary angiogram demonstrated significant areas of stenosis in the left main coronary artery (LMCA) and ostial left anterior descending (LAD) coronary artery. The patient was also found to have atretic bilateral internal mammary arteries as a consequence of his radiation therapy, rendering them unsuitable as grafts. Percutaneous coronary intervention (PCI) was thus performed with a successful outcome. To our knowledge, this is the first case of radiation-induced CAD of the LMCA with atretic internal mammary arteries treated successfully with PCI.
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spelling pubmed-72383662020-05-22 Radiation-Induced Left Main Coronary Artery Stenosis in a Patient with Atretic Internal Mammary Arteries Dogra, Siddhant Mahajan, Asha M. Jung, Albert Attubato, Michael Saric, Muhamed Shah, Alan Case Rep Cardiol Case Report Coronary artery disease (CAD) is a known potential complication of thoracic radiation treatment that typically affects the proximal segments of the coronary arteries, requiring coronary artery bypass grafting (CABG). We present a case of acute coronary syndrome occurring in a 57-year-old man with prior thoracic radiation therapy following resection of a chest wall chondrosarcoma. Coronary angiogram demonstrated significant areas of stenosis in the left main coronary artery (LMCA) and ostial left anterior descending (LAD) coronary artery. The patient was also found to have atretic bilateral internal mammary arteries as a consequence of his radiation therapy, rendering them unsuitable as grafts. Percutaneous coronary intervention (PCI) was thus performed with a successful outcome. To our knowledge, this is the first case of radiation-induced CAD of the LMCA with atretic internal mammary arteries treated successfully with PCI. Hindawi 2020-03-11 /pmc/articles/PMC7238366/ /pubmed/32455030 http://dx.doi.org/10.1155/2020/7970305 Text en Copyright © 2020 Siddhant Dogra et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Dogra, Siddhant
Mahajan, Asha M.
Jung, Albert
Attubato, Michael
Saric, Muhamed
Shah, Alan
Radiation-Induced Left Main Coronary Artery Stenosis in a Patient with Atretic Internal Mammary Arteries
title Radiation-Induced Left Main Coronary Artery Stenosis in a Patient with Atretic Internal Mammary Arteries
title_full Radiation-Induced Left Main Coronary Artery Stenosis in a Patient with Atretic Internal Mammary Arteries
title_fullStr Radiation-Induced Left Main Coronary Artery Stenosis in a Patient with Atretic Internal Mammary Arteries
title_full_unstemmed Radiation-Induced Left Main Coronary Artery Stenosis in a Patient with Atretic Internal Mammary Arteries
title_short Radiation-Induced Left Main Coronary Artery Stenosis in a Patient with Atretic Internal Mammary Arteries
title_sort radiation-induced left main coronary artery stenosis in a patient with atretic internal mammary arteries
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238366/
https://www.ncbi.nlm.nih.gov/pubmed/32455030
http://dx.doi.org/10.1155/2020/7970305
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