Cargando…
A two-compartment model of synaptic computation and plasticity
The synapse is typically viewed as a single compartment, which acts as a linear gain controller on incoming input. Traditional plasticity rules enable this gain control to be dynamically optimized by Hebbian activity. Whilst this view nicely captures postsynaptic function, it neglects the non-linear...
Autores principales: | Tong, Rudi, Emptage, Nigel J., Padamsey, Zahid |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238589/ https://www.ncbi.nlm.nih.gov/pubmed/32434549 http://dx.doi.org/10.1186/s13041-020-00617-1 |
Ejemplares similares
-
Imaging synaptic plasticity
por: Padamsey, Zahid, et al.
Publicado: (2011) -
Optical Quantal Analysis Using Ca(2+) Indicators: A Robust Method for Assessing Transmitter Release Probability at Excitatory Synapses by Imaging Single Glutamate Release Events
por: Padamsey, Zahid, et al.
Publicado: (2019) -
Glutamate is required for depression but not potentiation of long-term presynaptic function
por: Padamsey, Zahid, et al.
Publicado: (2017) -
Synaptic Transmission Optimization Predicts Expression Loci of Long-Term Plasticity
por: Costa, Rui Ponte, et al.
Publicado: (2017) -
Activity-Dependent Exocytosis of Lysosomes Regulates the Structural Plasticity of Dendritic Spines
por: Padamsey, Zahid, et al.
Publicado: (2017)