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Role of PKCε in the epithelial-mesenchymal transition induced by FGFR2 isoform switch

BACKGROUND: The epithelial isoform of the fibroblast growth factor receptor 2 (FGFR2b) controls the entire program of keratinocyte differentiation via the sequential involvement of protein kinase C (PKC) δ and PKCα. In contrast, the FGFR2 isoform switch and the aberrant expression of the mesenchymal...

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Detalles Bibliográficos
Autores principales: Ranieri, Danilo, Nanni, Monica, Persechino, Flavia, Torrisi, Maria Rosaria, Belleudi, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238605/
https://www.ncbi.nlm.nih.gov/pubmed/32429937
http://dx.doi.org/10.1186/s12964-020-00582-1