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Role of PKCε in the epithelial-mesenchymal transition induced by FGFR2 isoform switch
BACKGROUND: The epithelial isoform of the fibroblast growth factor receptor 2 (FGFR2b) controls the entire program of keratinocyte differentiation via the sequential involvement of protein kinase C (PKC) δ and PKCα. In contrast, the FGFR2 isoform switch and the aberrant expression of the mesenchymal...
Autores principales: | Ranieri, Danilo, Nanni, Monica, Persechino, Flavia, Torrisi, Maria Rosaria, Belleudi, Francesca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238605/ https://www.ncbi.nlm.nih.gov/pubmed/32429937 http://dx.doi.org/10.1186/s12964-020-00582-1 |
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