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Using a chimeric respiratory chain and EPR spectroscopy to determine the origin of semiquinone species previously assigned to mitochondrial complex I
BACKGROUND: For decades, semiquinone intermediates have been suggested to play an essential role in catalysis by one of the most enigmatic proton-pumping enzymes, respiratory complex I, and different mechanisms have been proposed on their basis. However, the difficulty in investigating complex I sem...
Autores principales: | Wright, John J., Fedor, Justin G., Hirst, Judy, Roessler, Maxie M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238650/ https://www.ncbi.nlm.nih.gov/pubmed/32429970 http://dx.doi.org/10.1186/s12915-020-00768-6 |
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