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A Rare Cause of Acute Pancreatitis in a Transgender Female
Acute pancreatitis is defined as an acute inflammation of the pancreas and is most commonly caused by gallstones and alcohol followed by elevated triglycerides and medications. Estrogen as a cause of secondary hypertriglyceridemic pancreatitis is a rare but known phenomenon in females on hormonal th...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238772/ https://www.ncbi.nlm.nih.gov/pubmed/32406257 http://dx.doi.org/10.1177/2324709620921333 |
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author | Shipley, Lindsey C. Steele, David T. Wilcox, Charles M. Burski, Chad M. |
author_facet | Shipley, Lindsey C. Steele, David T. Wilcox, Charles M. Burski, Chad M. |
author_sort | Shipley, Lindsey C. |
collection | PubMed |
description | Acute pancreatitis is defined as an acute inflammation of the pancreas and is most commonly caused by gallstones and alcohol followed by elevated triglycerides and medications. Estrogen as a cause of secondary hypertriglyceridemic pancreatitis is a rare but known phenomenon in females on hormonal therapy; however, it is not well described in the transgender female population. In this article, we present a case of a 31-year-old transgender female who developed acute, severe pancreatitis after a few months of using estrogen as transition therapy. To our knowledge, this is the third case report of a transgender female presenting with acute pancreatitis secondary to estrogen. Long-term supraphysiologic doses of sex hormones are required to maintain secondary sex characteristics placing this population at a higher risk of developing acute pancreatitis. Further research is needed to determine risk and screening methods to prevent this side effect. |
format | Online Article Text |
id | pubmed-7238772 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-72387722020-06-01 A Rare Cause of Acute Pancreatitis in a Transgender Female Shipley, Lindsey C. Steele, David T. Wilcox, Charles M. Burski, Chad M. J Investig Med High Impact Case Rep Case Report Acute pancreatitis is defined as an acute inflammation of the pancreas and is most commonly caused by gallstones and alcohol followed by elevated triglycerides and medications. Estrogen as a cause of secondary hypertriglyceridemic pancreatitis is a rare but known phenomenon in females on hormonal therapy; however, it is not well described in the transgender female population. In this article, we present a case of a 31-year-old transgender female who developed acute, severe pancreatitis after a few months of using estrogen as transition therapy. To our knowledge, this is the third case report of a transgender female presenting with acute pancreatitis secondary to estrogen. Long-term supraphysiologic doses of sex hormones are required to maintain secondary sex characteristics placing this population at a higher risk of developing acute pancreatitis. Further research is needed to determine risk and screening methods to prevent this side effect. SAGE Publications 2020-05-14 /pmc/articles/PMC7238772/ /pubmed/32406257 http://dx.doi.org/10.1177/2324709620921333 Text en © 2020 American Federation for Medical Research https://creativecommons.org/licenses/by/4.0/ This article is distributed under the terms of the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Case Report Shipley, Lindsey C. Steele, David T. Wilcox, Charles M. Burski, Chad M. A Rare Cause of Acute Pancreatitis in a Transgender Female |
title | A Rare Cause of Acute Pancreatitis in a Transgender Female |
title_full | A Rare Cause of Acute Pancreatitis in a Transgender Female |
title_fullStr | A Rare Cause of Acute Pancreatitis in a Transgender Female |
title_full_unstemmed | A Rare Cause of Acute Pancreatitis in a Transgender Female |
title_short | A Rare Cause of Acute Pancreatitis in a Transgender Female |
title_sort | rare cause of acute pancreatitis in a transgender female |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238772/ https://www.ncbi.nlm.nih.gov/pubmed/32406257 http://dx.doi.org/10.1177/2324709620921333 |
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