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Synergy of GSK-J4 With Doxorubicin in KRAS-Mutant Anaplastic Thyroid Cancer
BACKGROUND: Anaplastic thyroid cancer is the most aggressive thyroid cancer and has a poor prognosis. At present, there is no effective treatment for it. METHODS: Here, we used different concentrations of GSK-J4 or a combination of GSK-J4 and doxorubicin to treat human Cal-62, 8505C, and 8305C anapl...
Autores principales: | Lin, Bo, Lu, Bing, Hsieh, I-yun, Liang, Zhen, Sun, Zicheng, Yi, Yang, Lv, Weiming, Zhao, Wei, Li, Jie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239034/ https://www.ncbi.nlm.nih.gov/pubmed/32477122 http://dx.doi.org/10.3389/fphar.2020.00632 |
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