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Prioritization of SARS-CoV-2 epitopes using a pan-HLA and global population inference approach

SARS-CoV-2 T cell response assessment and vaccine development may benefit from an approach that considers the global landscape of the human leukocyte antigen (HLA) proteins. We predicted the binding affinity between 9-mer and 15-mer peptides from the SARS-CoV-2 peptidome for 9,360 class I and 8,445...

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Detalles Bibliográficos
Autores principales: Campbell, Katie M., Steiner, Gabriela, Wells, Daniel K., Ribas, Antoni, Kalbasi, Anusha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239055/
https://www.ncbi.nlm.nih.gov/pubmed/32511325
http://dx.doi.org/10.1101/2020.03.30.016931