Applications and explorations of CRISPR/Cas9 in CAR T-cell therapy

Chimeric antigen receptor(CAR) T-cell therapy has shown remarkable effects and promising prospects in patients with refractory or relapsed malignancies, pending further progress in the next-generation CAR T cells with more optimized structure, enhanced efficacy and reduced toxicities. The clustered...

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Detalles Bibliográficos
Autores principales: Li, Chenggong, Mei, Heng, Hu, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Rev Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239310/
https://www.ncbi.nlm.nih.gov/pubmed/31950135
http://dx.doi.org/10.1093/bfgp/elz042

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