Inflammasome-mediated antagonism of type I interferon enhances Rickettsia pathogenesis

The innate immune system fights infection with inflammasomes and interferons. Facultative bacterial pathogens that inhabit the host cytosol avoid inflammasomes(1–6) and are often insensitive to type I interferons (IFN-I), but are restricted by IFN-γ(7–11). However, it remains unclear how obligate cy...

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Detalles Bibliográficos
Autores principales: Burke, Thomas P., Engström, Patrik, Chavez, Roberto A., Fonbuena, Joshua A., Vance, Russell E., Welch, Matthew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239376/
https://www.ncbi.nlm.nih.gov/pubmed/32123346
http://dx.doi.org/10.1038/s41564-020-0673-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239376/
https://www.ncbi.nlm.nih.gov/pubmed/32123346
http://dx.doi.org/10.1038/s41564-020-0673-5

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