Discordant rearrangement of primary and anamnestic CD8(+) T cell responses to influenza A viral epitopes upon exposure to bacterial superantigens: Implications for prophylactic vaccination, heterosubtypic immunity and superinfections

Infection with (SAg)-producing bacteria may precede or follow infection with or vaccination against influenza A viruses (IAVs). However, how SAgs alter the breadth of IAV-specific CD8(+) T cell (T(CD8)) responses is unknown. Moreover, whether recall responses mediating heterosubtypic immunity to IAV...

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Detalles Bibliográficos
Autores principales: Meilleur, Courtney E., Memarnejadian, Arash, Shivji, Adil N., Benoit, Jenna M., Tuffs, Stephen W., Mele, Tina S., Singh, Bhagirath, Dikeakos, Jimmy D., Topham, David J., Mu, Hong-Hua, Bennink, Jack R., McCormick, John K., Haeryfar, S. M. Mansour
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239382/
https://www.ncbi.nlm.nih.gov/pubmed/32433711
http://dx.doi.org/10.1371/journal.ppat.1008393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239382/
https://www.ncbi.nlm.nih.gov/pubmed/32433711
http://dx.doi.org/10.1371/journal.ppat.1008393

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