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Idiopathic CD4+ T lymphocytopenia: A case report

Idiopathic CD4+ T lymphocytopenia (ICL) is a very rare immunodeficiency syndrome with an unexplained depletion of CD4+ T lymphocytes and no evidence of Human Immunodeficiency Virus (HIV) infection. Here we report a 29-year-old male patient who had severe ulcerative colitis with low level CD4+ count...

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Detalles Bibliográficos
Autores principales: Umamaheshwari, S, Sumana, MN, Shetty, MS, Gopal, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239395/
https://www.ncbi.nlm.nih.gov/pubmed/31898594
http://dx.doi.org/10.4103/jpgm.JPGM_324_19
Descripción
Sumario:Idiopathic CD4+ T lymphocytopenia (ICL) is a very rare immunodeficiency syndrome with an unexplained depletion of CD4+ T lymphocytes and no evidence of Human Immunodeficiency Virus (HIV) infection. Here we report a 29-year-old male patient who had severe ulcerative colitis with low level CD4+ count of 254 cells/mm(3), and had no evidence of HIV or Human T cell Lymphotrophic virus type I or II infections. He had recurrent Candidiasis infection and his CD4 count was just 53 cells/mm(3) after 3 months. The cause for the decline of CD4 T lymphocytes was unknown.