Apoptosis induction and proliferation inhibition by silibinin encapsulated in nanoparticles in MIA PaCa-2 cancer cells and deregulation of some miRNAs

OBJECTIVE(S): Silibinin, as an herbal compound, has anti-cancer activity. Because of low solubility of silibinin in water and body fluids, it was encapsulated in polymersome nanoparticles and its effects were evaluated on pancreatic cancer cells and cancer stem cells. MATERIALS AND METHODS: MIA PaCa...

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Detalles Bibliográficos
Autores principales: Khakinezhad Tehrani, Fatemeh, Ranji, Najmeh, Kouhkan, Fatemeh, Hosseinzadeh, Simzar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239422/
https://www.ncbi.nlm.nih.gov/pubmed/32489562
http://dx.doi.org/10.22038/ijbms.2020.39427.9349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239422/
https://www.ncbi.nlm.nih.gov/pubmed/32489562
http://dx.doi.org/10.22038/ijbms.2020.39427.9349

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