Synergistic actions of v-SNARE transmembrane domains and membrane-curvature modifying lipids in neurotransmitter release

Vesicle fusion is mediated by assembly of SNARE proteins between opposing membranes. While previous work suggested an active role of SNARE transmembrane domains (TMDs) in promoting membrane merger (Dhara et al., 2016), the underlying mechanism remained elusive. Here, we show that naturally-occurring...

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Detalles Bibliográficos
Autores principales: Dhara, Madhurima, Mantero Martinez, Maria, Makke, Mazen, Schwarz, Yvonne, Mohrmann, Ralf, Bruns, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239655/
https://www.ncbi.nlm.nih.gov/pubmed/32391794
http://dx.doi.org/10.7554/eLife.55152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239655/
https://www.ncbi.nlm.nih.gov/pubmed/32391794
http://dx.doi.org/10.7554/eLife.55152

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