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Loss of Ena/VASP interferes with lamellipodium architecture, motility and integrin-dependent adhesion

Cell migration entails networks and bundles of actin filaments termed lamellipodia and microspikes or filopodia, respectively, as well as focal adhesions, all of which recruit Ena/VASP family members hitherto thought to antagonize efficient cell motility. However, we find these proteins to act as po...

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Detalles Bibliográficos
Autores principales:	Damiano-Guercio, Julia, Kurzawa, Laëtitia, Mueller, Jan, Dimchev, Georgi, Schaks, Matthias, Nemethova, Maria, Pokrant, Thomas, Brühmann, Stefan, Linkner, Joern, Blanchoin, Laurent, Sixt, Michael, Rottner, Klemens, Faix, Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2020
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239657/ https://www.ncbi.nlm.nih.gov/pubmed/32391788 http://dx.doi.org/10.7554/eLife.55351

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