Position paper on the preparation of immune plasma to be used in the treatment of patients with COVID-19

Passive immunotherapy with plasma derived from patients convalescent from SARS-CoV-2 infection can be a promising approach in the treatment of COVID-19 patients. It is important that Blood Establishments are prepared to satisfy requests for immune plasma by defining the requirements applicable to pl...

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Detalles Bibliográficos
Autores principales: Accorsi, Patrizia, Berti, Pierluigi, de Angelis, Vincenzo, De Silvestro, Giustina, Mascaretti, Luca, Ostuni, Angelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239775/
https://www.ncbi.nlm.nih.gov/pubmed/32532691
http://dx.doi.org/10.1016/j.transci.2020.102817
Descripción
Sumario:Passive immunotherapy with plasma derived from patients convalescent from SARS-CoV-2 infection can be a promising approach in the treatment of COVID-19 patients. It is important that Blood Establishments are prepared to satisfy requests for immune plasma by defining the requirements applicable to plasma donors and the standards for preparation, qualification, storage, distribution and control of use of the product. This position paper is aimed to give recommendations on biological characteristics of a plasma preparation from convalescent donors and to support the evaluation of this therapeutic approach in more rigorous investigations.

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