Metalation: nature’s challenge in bioinorganic chemistry

The association of proteins with metals, metalation, is challenging because the tightest binding metals are rarely the correct ones. Inside cells, correct metalation is enabled by controlled bioavailability plus extra mechanisms for tricky combinations such as iron and manganese.

Detalles Bibliográficos
Autores principales: Robinson, Nigel J., Glasfeld, Arthur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239837/
https://www.ncbi.nlm.nih.gov/pubmed/32333210
http://dx.doi.org/10.1007/s00775-020-01790-3
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author Robinson, Nigel J.
Glasfeld, Arthur
author_facet Robinson, Nigel J.
Glasfeld, Arthur
author_sort Robinson, Nigel J.
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description The association of proteins with metals, metalation, is challenging because the tightest binding metals are rarely the correct ones. Inside cells, correct metalation is enabled by controlled bioavailability plus extra mechanisms for tricky combinations such as iron and manganese.
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spelling pubmed-72398372020-05-27 Metalation: nature’s challenge in bioinorganic chemistry Robinson, Nigel J. Glasfeld, Arthur J Biol Inorg Chem Commentary The association of proteins with metals, metalation, is challenging because the tightest binding metals are rarely the correct ones. Inside cells, correct metalation is enabled by controlled bioavailability plus extra mechanisms for tricky combinations such as iron and manganese. Springer Berlin Heidelberg 2020-04-24 2020 /pmc/articles/PMC7239837/ /pubmed/32333210 http://dx.doi.org/10.1007/s00775-020-01790-3 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Commentary
Robinson, Nigel J.
Glasfeld, Arthur
Metalation: nature’s challenge in bioinorganic chemistry
title Metalation: nature’s challenge in bioinorganic chemistry
title_full Metalation: nature’s challenge in bioinorganic chemistry
title_fullStr Metalation: nature’s challenge in bioinorganic chemistry
title_full_unstemmed Metalation: nature’s challenge in bioinorganic chemistry
title_short Metalation: nature’s challenge in bioinorganic chemistry
title_sort metalation: nature’s challenge in bioinorganic chemistry
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239837/
https://www.ncbi.nlm.nih.gov/pubmed/32333210
http://dx.doi.org/10.1007/s00775-020-01790-3
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