ERK Activity in Immature Leukemic Cells Drives Clonal Selection during Induction Therapy for Acute Myeloid Leukemia

Selection of resistant clones following intensive chemotherapy is a common obstacle for cure in many cancers, particularly in acute myeloid leukemia (AML). In AML, clone-specific sensitivity to chemotherapy varies even within the same patient. Multiple mutations and genetic aberrations are associate...

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Detalles Bibliográficos
Autores principales: Hayun, Michal, Zaatra, Maria, Itzkovich, Chen, Sahar, Dvora, Rosenberg, Dina, Filatova, Margarita, Ringelstein-Harlev, Shimrit, Baris, Hagit, Moustafa-Hawash, Nivin, Louria-Hayon, Igal, Ofran, Yishai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239856/
https://www.ncbi.nlm.nih.gov/pubmed/32433559
http://dx.doi.org/10.1038/s41598-020-65061-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239856/
https://www.ncbi.nlm.nih.gov/pubmed/32433559
http://dx.doi.org/10.1038/s41598-020-65061-6

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