Tunable Fe(3)O(4) Nanorods for Enhanced Magnetic Hyperthermia Performance

Magnetic hyperthermia is one of the most promising techniques for treating gynecological cancer, where magnetite (Fe(3)O(4)) is the most common nanomaterial used as a magnetic hyperthermia agent. Here, we demonstrate that optimal Fe(3)O(4) nanorods (NRs) can act as a magnetic hyperthermia agent with...

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Detalles Bibliográficos
Autores principales: Yang, Yongxiu, Huang, Mengwei, Qian, Jinmei, Gao, Daqiang, Liang, Xiaolei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239883/
https://www.ncbi.nlm.nih.gov/pubmed/32433578
http://dx.doi.org/10.1038/s41598-020-65095-w
Descripción
Sumario:Magnetic hyperthermia is one of the most promising techniques for treating gynecological cancer, where magnetite (Fe(3)O(4)) is the most common nanomaterial used as a magnetic hyperthermia agent. Here, we demonstrate that optimal Fe(3)O(4) nanorods (NRs) can act as a magnetic hyperthermia agent with higher specific absorption rate (SAR), which is mostly attributed to their enhanced surface anisotropy. As a result, Fe(3)O(4) NRs could effectively hinder the growth of gynecological cancer cells in nude mice models, again demonstrating its good magnetic heating properties. These results provide a powerful basis for the development of an ideal magnetic hyperthermia agent with enhanced SAR, thereby effectively treating gynecological cancer in clinical practice.

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