Tunable Fe(3)O(4) Nanorods for Enhanced Magnetic Hyperthermia Performance

Magnetic hyperthermia is one of the most promising techniques for treating gynecological cancer, where magnetite (Fe(3)O(4)) is the most common nanomaterial used as a magnetic hyperthermia agent. Here, we demonstrate that optimal Fe(3)O(4) nanorods (NRs) can act as a magnetic hyperthermia agent with...

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Autores principales: Yang, Yongxiu, Huang, Mengwei, Qian, Jinmei, Gao, Daqiang, Liang, Xiaolei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239883/
https://www.ncbi.nlm.nih.gov/pubmed/32433578
http://dx.doi.org/10.1038/s41598-020-65095-w
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author Yang, Yongxiu
Huang, Mengwei
Qian, Jinmei
Gao, Daqiang
Liang, Xiaolei
author_facet Yang, Yongxiu
Huang, Mengwei
Qian, Jinmei
Gao, Daqiang
Liang, Xiaolei
author_sort Yang, Yongxiu
collection PubMed
description Magnetic hyperthermia is one of the most promising techniques for treating gynecological cancer, where magnetite (Fe(3)O(4)) is the most common nanomaterial used as a magnetic hyperthermia agent. Here, we demonstrate that optimal Fe(3)O(4) nanorods (NRs) can act as a magnetic hyperthermia agent with higher specific absorption rate (SAR), which is mostly attributed to their enhanced surface anisotropy. As a result, Fe(3)O(4) NRs could effectively hinder the growth of gynecological cancer cells in nude mice models, again demonstrating its good magnetic heating properties. These results provide a powerful basis for the development of an ideal magnetic hyperthermia agent with enhanced SAR, thereby effectively treating gynecological cancer in clinical practice.
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spelling pubmed-72398832020-05-29 Tunable Fe(3)O(4) Nanorods for Enhanced Magnetic Hyperthermia Performance Yang, Yongxiu Huang, Mengwei Qian, Jinmei Gao, Daqiang Liang, Xiaolei Sci Rep Article Magnetic hyperthermia is one of the most promising techniques for treating gynecological cancer, where magnetite (Fe(3)O(4)) is the most common nanomaterial used as a magnetic hyperthermia agent. Here, we demonstrate that optimal Fe(3)O(4) nanorods (NRs) can act as a magnetic hyperthermia agent with higher specific absorption rate (SAR), which is mostly attributed to their enhanced surface anisotropy. As a result, Fe(3)O(4) NRs could effectively hinder the growth of gynecological cancer cells in nude mice models, again demonstrating its good magnetic heating properties. These results provide a powerful basis for the development of an ideal magnetic hyperthermia agent with enhanced SAR, thereby effectively treating gynecological cancer in clinical practice. Nature Publishing Group UK 2020-05-20 /pmc/articles/PMC7239883/ /pubmed/32433578 http://dx.doi.org/10.1038/s41598-020-65095-w Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Yang, Yongxiu
Huang, Mengwei
Qian, Jinmei
Gao, Daqiang
Liang, Xiaolei
Tunable Fe(3)O(4) Nanorods for Enhanced Magnetic Hyperthermia Performance
title Tunable Fe(3)O(4) Nanorods for Enhanced Magnetic Hyperthermia Performance
title_full Tunable Fe(3)O(4) Nanorods for Enhanced Magnetic Hyperthermia Performance
title_fullStr Tunable Fe(3)O(4) Nanorods for Enhanced Magnetic Hyperthermia Performance
title_full_unstemmed Tunable Fe(3)O(4) Nanorods for Enhanced Magnetic Hyperthermia Performance
title_short Tunable Fe(3)O(4) Nanorods for Enhanced Magnetic Hyperthermia Performance
title_sort tunable fe(3)o(4) nanorods for enhanced magnetic hyperthermia performance
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239883/
https://www.ncbi.nlm.nih.gov/pubmed/32433578
http://dx.doi.org/10.1038/s41598-020-65095-w
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