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Identification of Alternative Allosteric Sites in Glycolytic Enzymes for Potential Use as Species-Specific Drug Targets

Three allosteric glycolytic enzymes, phosphofructokinase, glyceraldehyde-3 phosphate dehydrogenase and pyruvate kinase, associated with bacterial, parasitic and human species, were explored to identify potential allosteric sites that would be used as prime targets for species-specific drug design pu...

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Detalles Bibliográficos
Autores principales: Ayyildiz, Merve, Celiker, Serkan, Ozhelvaci, Fatih, Akten, E. Demet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240002/
https://www.ncbi.nlm.nih.gov/pubmed/32478093
http://dx.doi.org/10.3389/fmolb.2020.00088

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