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Gut-Derived Serotonin Contributes to the Progression of Non-Alcoholic Steatohepatitis via the Liver HTR2A/PPARγ2 Pathway

The precipitous increase in occurrence of non-alcoholic steatohepatitis (NASH) is a serious threat to public health worldwide. The pathogenesis of NASH has not yet been thoroughly studied. We aimed to elucidate the interplay between serotonin (5-hydroxytryptamine, 5-HT) and NASH. The serum 5-HT leve...

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Detalles Bibliográficos
Autores principales:	Wang, Lulu, Fan, Xiangcheng, Han, Jichun, Cai, Minxuan, Wang, Xiaozhong, Wang, Yan, Shang, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240039/ https://www.ncbi.nlm.nih.gov/pubmed/32477107 http://dx.doi.org/10.3389/fphar.2020.00553

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