Electroporation of NKG2D RNA CAR Improves Vγ9Vδ2 T Cell Responses against Human Solid Tumor Xenografts

Vγ9Vδ2 T cell-based anticancer immunotherapy has shown some promise in early-phase clinical trials but there is still large room for improvement. Using the extracellular domain of the human NKG2D, a stimulatory receptor expressed by Vγ9Vδ2 T cells, we constructed NKG2D ligand-specific chimeric antig...

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Detalles Bibliográficos
Autores principales: Ang, Wei Xia, Ng, Yu Yang, Xiao, Lin, Chen, Can, Li, Zhendong, Chi, Zhixia, Tay, Johan Chin-Kang, Tan, Wee Kiat, Zeng, Jieming, Toh, Han Chong, Wang, Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240063/
https://www.ncbi.nlm.nih.gov/pubmed/32462079
http://dx.doi.org/10.1016/j.omto.2020.04.013

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