A Rapidly Evolving Polybasic Motif Modulates Bacterial Detection by Guanylate Binding Proteins

Cell-autonomous immunity relies on the rapid detection of invasive pathogens by host proteins. Guanylate binding proteins (GBPs) have emerged as key mediators of vertebrate immune defense through their ability to recognize a diverse array of intracellular pathogens and pathogen-containing cellular c...

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Detalles Bibliográficos
Autores principales: Kohler, Kristin M., Kutsch, Miriam, Piro, Anthony S., Wallace, Graham D., Coers, Jörn, Barber, Matthew F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240152/
https://www.ncbi.nlm.nih.gov/pubmed/32430466
http://dx.doi.org/10.1128/mBio.00340-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240152/
https://www.ncbi.nlm.nih.gov/pubmed/32430466
http://dx.doi.org/10.1128/mBio.00340-20

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