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A Rapidly Evolving Polybasic Motif Modulates Bacterial Detection by Guanylate Binding Proteins
Cell-autonomous immunity relies on the rapid detection of invasive pathogens by host proteins. Guanylate binding proteins (GBPs) have emerged as key mediators of vertebrate immune defense through their ability to recognize a diverse array of intracellular pathogens and pathogen-containing cellular c...
Autores principales: | Kohler, Kristin M., Kutsch, Miriam, Piro, Anthony S., Wallace, Graham D., Coers, Jörn, Barber, Matthew F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240152/ https://www.ncbi.nlm.nih.gov/pubmed/32430466 http://dx.doi.org/10.1128/mBio.00340-20 |
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