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Tissue Responses to Shiga Toxin in Human Intestinal Organoids

BACKGROUND & AIMS: Shiga toxin (Stx)-producing Escherichia coli (eg, O157:H7) infection produces bloody diarrhea, while Stx inhibits protein synthesis and causes the life-threatening systemic complication of hemolytic uremic syndrome. The murine intestinal tract is resistant to O157:H7 and Stx,...

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Detalles Bibliográficos
Autores principales:	Pradhan, Suman, Karve, Sayali S., Weiss, Alison A., Hawkins, Jennifer, Poling, Holly M., Helmrath, Michael A., Wells, James M., McCauley, Heather A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240222/ https://www.ncbi.nlm.nih.gov/pubmed/32145469 http://dx.doi.org/10.1016/j.jcmgh.2020.02.006

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