A Physiology-Based Model of Bile Acid Distribution and Metabolism Under Healthy and Pathologic Conditions in Human Beings

BACKGROUND & AIMS: Disturbances of the enterohepatic circulation of bile acids (BAs) are seen in a number of clinically important conditions, including metabolic disorders, hepatic impairment, diarrhea, and gallstone disease. To facilitate the exploration of underlying pathogenic mechanisms, we...

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Detalles Bibliográficos
Autores principales: Voronova, Veronika, Sokolov, Victor, Al-Khaifi, Amani, Straniero, Sara, Kumar, Chanchal, Peskov, Kirill, Helmlinger, Gabriel, Rudling, Mats, Angelin, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240226/
https://www.ncbi.nlm.nih.gov/pubmed/32112828
http://dx.doi.org/10.1016/j.jcmgh.2020.02.005

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