COVID-19: the vasculature unleashed

On the basis of emerging evidence from patients with COVID-19, we postulate that endothelial cells are essential contributors to the initiation and propagation of severe COVID-19. Here, we discuss current insights into the link between endothelial cells, viral infection and inflammatory changes and...

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Autores principales: Teuwen, Laure-Anne, Geldhof, Vincent, Pasut, Alessandra, Carmeliet, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240244/
https://www.ncbi.nlm.nih.gov/pubmed/32439870
http://dx.doi.org/10.1038/s41577-020-0343-0
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author Teuwen, Laure-Anne
Geldhof, Vincent
Pasut, Alessandra
Carmeliet, Peter
author_facet Teuwen, Laure-Anne
Geldhof, Vincent
Pasut, Alessandra
Carmeliet, Peter
author_sort Teuwen, Laure-Anne
collection PubMed
description On the basis of emerging evidence from patients with COVID-19, we postulate that endothelial cells are essential contributors to the initiation and propagation of severe COVID-19. Here, we discuss current insights into the link between endothelial cells, viral infection and inflammatory changes and propose novel therapeutic strategies.
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spelling pubmed-72402442020-05-21 COVID-19: the vasculature unleashed Teuwen, Laure-Anne Geldhof, Vincent Pasut, Alessandra Carmeliet, Peter Nat Rev Immunol Comment On the basis of emerging evidence from patients with COVID-19, we postulate that endothelial cells are essential contributors to the initiation and propagation of severe COVID-19. Here, we discuss current insights into the link between endothelial cells, viral infection and inflammatory changes and propose novel therapeutic strategies. Nature Publishing Group UK 2020-05-21 2020 /pmc/articles/PMC7240244/ /pubmed/32439870 http://dx.doi.org/10.1038/s41577-020-0343-0 Text en © Springer Nature Limited 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Comment
Teuwen, Laure-Anne
Geldhof, Vincent
Pasut, Alessandra
Carmeliet, Peter
COVID-19: the vasculature unleashed
title COVID-19: the vasculature unleashed
title_full COVID-19: the vasculature unleashed
title_fullStr COVID-19: the vasculature unleashed
title_full_unstemmed COVID-19: the vasculature unleashed
title_short COVID-19: the vasculature unleashed
title_sort covid-19: the vasculature unleashed
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240244/
https://www.ncbi.nlm.nih.gov/pubmed/32439870
http://dx.doi.org/10.1038/s41577-020-0343-0
work_keys_str_mv AT teuwenlaureanne covid19thevasculatureunleashed
AT geldhofvincent covid19thevasculatureunleashed
AT pasutalessandra covid19thevasculatureunleashed
AT carmelietpeter covid19thevasculatureunleashed

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