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Pulmonary mucormycosis with extensive bronchial necrosis and bronchomediastinal fistula: A case report and review

Mucormycosis is a life-threatening infection caused by fungi in the Mucorales species. It most often affects immunocompromised hosts, including diabetics patients. It can affect a variety of organ systems with pulmonary manifestations being the second most common. In severe cases, significant bronch...

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Detalles Bibliográficos
Autores principales: Seifert, S., Wiley, J., Kirkham, J., Lena, S., Schiers, K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240283/
https://www.ncbi.nlm.nih.gov/pubmed/32461882
http://dx.doi.org/10.1016/j.rmcr.2020.101082
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author Seifert, S.
Wiley, J.
Kirkham, J.
Lena, S.
Schiers, K.
author_facet Seifert, S.
Wiley, J.
Kirkham, J.
Lena, S.
Schiers, K.
author_sort Seifert, S.
collection PubMed
description Mucormycosis is a life-threatening infection caused by fungi in the Mucorales species. It most often affects immunocompromised hosts, including diabetics patients. It can affect a variety of organ systems with pulmonary manifestations being the second most common. In severe cases, significant bronchial necrosis and angioinvasion can be seen. Due to its rarity, such extensive cases are not often reported in literature. We present a case of a 32-year-old man who presented with severe bronchial necrosis, including bronchomediastinal fistula, due to Rhizopus. Despite prompt treatment, he developed massive hemoptysis from invasion of the pulmonary vasculature and died. We also provide a brief review of mucormycosis.
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spelling pubmed-72402832020-05-26 Pulmonary mucormycosis with extensive bronchial necrosis and bronchomediastinal fistula: A case report and review Seifert, S. Wiley, J. Kirkham, J. Lena, S. Schiers, K. Respir Med Case Rep Case Report Mucormycosis is a life-threatening infection caused by fungi in the Mucorales species. It most often affects immunocompromised hosts, including diabetics patients. It can affect a variety of organ systems with pulmonary manifestations being the second most common. In severe cases, significant bronchial necrosis and angioinvasion can be seen. Due to its rarity, such extensive cases are not often reported in literature. We present a case of a 32-year-old man who presented with severe bronchial necrosis, including bronchomediastinal fistula, due to Rhizopus. Despite prompt treatment, he developed massive hemoptysis from invasion of the pulmonary vasculature and died. We also provide a brief review of mucormycosis. Elsevier 2020-05-06 /pmc/articles/PMC7240283/ /pubmed/32461882 http://dx.doi.org/10.1016/j.rmcr.2020.101082 Text en © 2020 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Seifert, S.
Wiley, J.
Kirkham, J.
Lena, S.
Schiers, K.
Pulmonary mucormycosis with extensive bronchial necrosis and bronchomediastinal fistula: A case report and review
title Pulmonary mucormycosis with extensive bronchial necrosis and bronchomediastinal fistula: A case report and review
title_full Pulmonary mucormycosis with extensive bronchial necrosis and bronchomediastinal fistula: A case report and review
title_fullStr Pulmonary mucormycosis with extensive bronchial necrosis and bronchomediastinal fistula: A case report and review
title_full_unstemmed Pulmonary mucormycosis with extensive bronchial necrosis and bronchomediastinal fistula: A case report and review
title_short Pulmonary mucormycosis with extensive bronchial necrosis and bronchomediastinal fistula: A case report and review
title_sort pulmonary mucormycosis with extensive bronchial necrosis and bronchomediastinal fistula: a case report and review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240283/
https://www.ncbi.nlm.nih.gov/pubmed/32461882
http://dx.doi.org/10.1016/j.rmcr.2020.101082
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