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Wear Resistant Nanocomposites Based on Biomedical Grade UHMWPE Paraffin Oil and Carbon Nano-Filler: Preliminary Biocompatibility and Antibacterial Activity Investigation

In the present paper, we investigate the effectiveness of nanocomposites (composed of ultra-high molecular weight polyethylene (UHMWPE) mixed with carbon nano-filler (CNF) and medical grade paraffin oil (PO), from the biological point of view. Wear measurements were carried out without (air) and wit...

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Detalles Bibliográficos
Autores principales: Catauro, Michelina, Scolaro, Cristina, Dal Poggetto, Giovanni, Pacifico, Severina, Visco, Annamaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240565/
https://www.ncbi.nlm.nih.gov/pubmed/32331367
http://dx.doi.org/10.3390/polym12040978
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author Catauro, Michelina
Scolaro, Cristina
Dal Poggetto, Giovanni
Pacifico, Severina
Visco, Annamaria
author_facet Catauro, Michelina
Scolaro, Cristina
Dal Poggetto, Giovanni
Pacifico, Severina
Visco, Annamaria
author_sort Catauro, Michelina
collection PubMed
description In the present paper, we investigate the effectiveness of nanocomposites (composed of ultra-high molecular weight polyethylene (UHMWPE) mixed with carbon nano-filler (CNF) and medical grade paraffin oil (PO), from the biological point of view. Wear measurements were carried out without (air) and with lubricant (distilled water, natural, and artificial lubricant), and antibacterial activity and cytotoxicity were evaluated. The results highlighted that the presence of CNF is important in the nanocomposite formulation because it reduces the wear rate and prevents oxidative degradation during its processing. An amount of 1.0 wt % of CNF is best because it reaches the optimal distribution within the polymeric matrix, resulting in the best wear resistant, bio-active, and anti-bacterial nanocomposite among all investigated samples.
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spelling pubmed-72405652020-06-11 Wear Resistant Nanocomposites Based on Biomedical Grade UHMWPE Paraffin Oil and Carbon Nano-Filler: Preliminary Biocompatibility and Antibacterial Activity Investigation Catauro, Michelina Scolaro, Cristina Dal Poggetto, Giovanni Pacifico, Severina Visco, Annamaria Polymers (Basel) Article In the present paper, we investigate the effectiveness of nanocomposites (composed of ultra-high molecular weight polyethylene (UHMWPE) mixed with carbon nano-filler (CNF) and medical grade paraffin oil (PO), from the biological point of view. Wear measurements were carried out without (air) and with lubricant (distilled water, natural, and artificial lubricant), and antibacterial activity and cytotoxicity were evaluated. The results highlighted that the presence of CNF is important in the nanocomposite formulation because it reduces the wear rate and prevents oxidative degradation during its processing. An amount of 1.0 wt % of CNF is best because it reaches the optimal distribution within the polymeric matrix, resulting in the best wear resistant, bio-active, and anti-bacterial nanocomposite among all investigated samples. MDPI 2020-04-22 /pmc/articles/PMC7240565/ /pubmed/32331367 http://dx.doi.org/10.3390/polym12040978 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Catauro, Michelina
Scolaro, Cristina
Dal Poggetto, Giovanni
Pacifico, Severina
Visco, Annamaria
Wear Resistant Nanocomposites Based on Biomedical Grade UHMWPE Paraffin Oil and Carbon Nano-Filler: Preliminary Biocompatibility and Antibacterial Activity Investigation
title Wear Resistant Nanocomposites Based on Biomedical Grade UHMWPE Paraffin Oil and Carbon Nano-Filler: Preliminary Biocompatibility and Antibacterial Activity Investigation
title_full Wear Resistant Nanocomposites Based on Biomedical Grade UHMWPE Paraffin Oil and Carbon Nano-Filler: Preliminary Biocompatibility and Antibacterial Activity Investigation
title_fullStr Wear Resistant Nanocomposites Based on Biomedical Grade UHMWPE Paraffin Oil and Carbon Nano-Filler: Preliminary Biocompatibility and Antibacterial Activity Investigation
title_full_unstemmed Wear Resistant Nanocomposites Based on Biomedical Grade UHMWPE Paraffin Oil and Carbon Nano-Filler: Preliminary Biocompatibility and Antibacterial Activity Investigation
title_short Wear Resistant Nanocomposites Based on Biomedical Grade UHMWPE Paraffin Oil and Carbon Nano-Filler: Preliminary Biocompatibility and Antibacterial Activity Investigation
title_sort wear resistant nanocomposites based on biomedical grade uhmwpe paraffin oil and carbon nano-filler: preliminary biocompatibility and antibacterial activity investigation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240565/
https://www.ncbi.nlm.nih.gov/pubmed/32331367
http://dx.doi.org/10.3390/polym12040978
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