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Effect of the His-Tag Location on Decapping Scavenger Enzymes and Their Hydrolytic Activity toward Cap Analogs

[Image: see text] Decapping scavenger enzymes (DcpSs) are important players in mRNA degradation machinery and conserved in eukaryotes. Importantly, human DcpS is the recognized target for spinal muscular atrophy (SMA) and acute myeloid leukemia (AML) therapy, and has recently been connected to devel...

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Detalles Bibliográficos
Autores principales:	Ferenc-Mrozek, Aleksandra, Bojarska, Elzbieta, Stepinski, Janusz, Darzynkiewicz, Edward, Lukaszewicz, Maciej
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2020
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240826/ https://www.ncbi.nlm.nih.gov/pubmed/32455195 http://dx.doi.org/10.1021/acsomega.0c00304

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