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Multidisciplinary therapy strategy of precision medicine in clinical practice

The application of precision medicine concept in clinical work needs a period of practice and experience accumulation. The present article introduced an example of functioning approach named “multidisciplinary therapy strategy of precision medicine” (MDTS‐PM), clinical practice and process, decision...

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Detalles Bibliográficos
Autores principales: Qian, Mengjia, Li, Qian, Zhang, Miaomiao, Xu, Xiaojing, Shen, Qi, Chen, Hao, Wang, Xiangdong, Liu, Tianshu, Cheng, Yunfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240867/
https://www.ncbi.nlm.nih.gov/pubmed/32508051
http://dx.doi.org/10.1002/ctm2.15
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author Qian, Mengjia
Li, Qian
Zhang, Miaomiao
Xu, Xiaojing
Shen, Qi
Chen, Hao
Wang, Xiangdong
Liu, Tianshu
Cheng, Yunfeng
author_facet Qian, Mengjia
Li, Qian
Zhang, Miaomiao
Xu, Xiaojing
Shen, Qi
Chen, Hao
Wang, Xiangdong
Liu, Tianshu
Cheng, Yunfeng
author_sort Qian, Mengjia
collection PubMed
description The application of precision medicine concept in clinical work needs a period of practice and experience accumulation. The present article introduced an example of functioning approach named “multidisciplinary therapy strategy of precision medicine” (MDTS‐PM), clinical practice and process, decision‐making, and therapies. The MDTS‐PM integrates multidisciplinary experts and develops real‐time therapeutic strategy based on clinical phenomes and gene sequencing of tissue DNA and circulating DNA. The strength of MDTS‐PM is the combination of dynamical clinical phenomes, genetic information, diagnosis, and treatment to make the therapy more targeted and specific. MDTS‐PM provides comprehensive, whole‐process, and personalized diagnosis and treatment services for patients with complex cancer or complex drug resistance progression; provides guidance for further adjustment of drug use; and establishes a multidisciplinary cooperative team, improves the quality of clinical diagnosis and treatment, and optimizes the process of medical services.
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spelling pubmed-72408672020-06-01 Multidisciplinary therapy strategy of precision medicine in clinical practice Qian, Mengjia Li, Qian Zhang, Miaomiao Xu, Xiaojing Shen, Qi Chen, Hao Wang, Xiangdong Liu, Tianshu Cheng, Yunfeng Clin Transl Med Research Articles The application of precision medicine concept in clinical work needs a period of practice and experience accumulation. The present article introduced an example of functioning approach named “multidisciplinary therapy strategy of precision medicine” (MDTS‐PM), clinical practice and process, decision‐making, and therapies. The MDTS‐PM integrates multidisciplinary experts and develops real‐time therapeutic strategy based on clinical phenomes and gene sequencing of tissue DNA and circulating DNA. The strength of MDTS‐PM is the combination of dynamical clinical phenomes, genetic information, diagnosis, and treatment to make the therapy more targeted and specific. MDTS‐PM provides comprehensive, whole‐process, and personalized diagnosis and treatment services for patients with complex cancer or complex drug resistance progression; provides guidance for further adjustment of drug use; and establishes a multidisciplinary cooperative team, improves the quality of clinical diagnosis and treatment, and optimizes the process of medical services. John Wiley and Sons Inc. 2020-03-31 /pmc/articles/PMC7240867/ /pubmed/32508051 http://dx.doi.org/10.1002/ctm2.15 Text en © 2020 The Authors. Clinical and Translational Medicine published by John Wiley & Sons Australia, Ltd on behalf of Shanghai Institute of Clinical Bioinformatics This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Articles
Qian, Mengjia
Li, Qian
Zhang, Miaomiao
Xu, Xiaojing
Shen, Qi
Chen, Hao
Wang, Xiangdong
Liu, Tianshu
Cheng, Yunfeng
Multidisciplinary therapy strategy of precision medicine in clinical practice
title Multidisciplinary therapy strategy of precision medicine in clinical practice
title_full Multidisciplinary therapy strategy of precision medicine in clinical practice
title_fullStr Multidisciplinary therapy strategy of precision medicine in clinical practice
title_full_unstemmed Multidisciplinary therapy strategy of precision medicine in clinical practice
title_short Multidisciplinary therapy strategy of precision medicine in clinical practice
title_sort multidisciplinary therapy strategy of precision medicine in clinical practice
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240867/
https://www.ncbi.nlm.nih.gov/pubmed/32508051
http://dx.doi.org/10.1002/ctm2.15
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