Rhazyaminine from Rhazya stricta Inhibits Metastasis and Induces Apoptosis by Downregulating Bcl-2 Gene in MCF7 Cell Line

Background: The role of alkaloids isolated from Rhazya stricta Decne (Apocynaceae family) (RS) in targeting genes involved in cancer and metastasis remains to be elucidated. Objective: Identify and characterize new compounds from RS, which inhibit gene(s) involved in the survival, invasion, self-ren...

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Detalles Bibliográficos
Autores principales: Iqbal, Waqas, Alkarim, Saleh, Kamal, Tahseen, Choudhry, Hani, Sabir, Jamal, Bora, Roop S., Saini, Kulvinder S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240879/
https://www.ncbi.nlm.nih.gov/pubmed/30373413
http://dx.doi.org/10.1177/1534735418809901

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240879/
https://www.ncbi.nlm.nih.gov/pubmed/30373413
http://dx.doi.org/10.1177/1534735418809901

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