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Rhazyaminine from Rhazya stricta Inhibits Metastasis and Induces Apoptosis by Downregulating Bcl-2 Gene in MCF7 Cell Line
Background: The role of alkaloids isolated from Rhazya stricta Decne (Apocynaceae family) (RS) in targeting genes involved in cancer and metastasis remains to be elucidated. Objective: Identify and characterize new compounds from RS, which inhibit gene(s) involved in the survival, invasion, self-ren...
Autores principales: | Iqbal, Waqas, Alkarim, Saleh, Kamal, Tahseen, Choudhry, Hani, Sabir, Jamal, Bora, Roop S., Saini, Kulvinder S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240879/ https://www.ncbi.nlm.nih.gov/pubmed/30373413 http://dx.doi.org/10.1177/1534735418809901 |
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