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Statin inhibits large hepatitis delta antigen-Smad3 -twist-mediated epithelial-to-mesenchymal transition and hepatitis D virus secretion
BACKGROUND: Hepatitis D virus (HDV) infection may induce fulminant hepatitis in chronic hepatitis B patients (CHB) or rapid progression of CHB to cirrhosis or hepatocellular carcinoma. There is no effective treatment for HDV infection. HDV encodes small delta antigens (S-HDAg) and large delta antige...
Autores principales: | Liang, Yuh-Jin, Sun, Cheng-Pu, Hsu, Yu-Chen, Chen, Yi-Wen, Wang, I-An, Su, Chien-Wei, Tao, Mi-Hua, Wu, Jaw-Ching |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240974/ https://www.ncbi.nlm.nih.gov/pubmed/32434501 http://dx.doi.org/10.1186/s12929-020-00659-6 |
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