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Adipocytes promote tumor progression and induce PD-L1 expression via TNF-α/IL-6 signaling

BACKGROUND: Obesity confers increased risk for various types of cancer. PD-L1 is a key molecule in tumor immune evasion by inducing T cell exhaustion. The relationship between obesity and PD-L1 is still ambiguous. This study was designed to reveal the development of hepatocellular carcinoma and mela...

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Detalles Bibliográficos
Autores principales:	Li, Zhi, Zhang, Cai, Du, Jing-Xia, Zhao, Jia, Shi, Meng-Ting, Jin, Man-Wen, Liu, Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240984/ https://www.ncbi.nlm.nih.gov/pubmed/32477009 http://dx.doi.org/10.1186/s12935-020-01269-w

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