Optimal, minimax and admissible two-stage design for phase II oncology clinical trials

BACKGROUND: The article aims to compare the efficiency of minimax, optimal and admissible criteria in Simon’s and Fleming’s two-stage design. METHODS: Three parameter settings (p(1)-p(0) = 0.25–0.05, 0.30–0.10, 0.50–0.30) are designed to compare the maximum sample size, the critical values and the e...

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Detalles Bibliográficos
Autores principales: Qin, Fei, Wu, Jingwei, Chen, Feng, Wei, Yongyue, Zhao, Yang, Jiang, Zhiwei, Bai, Jianling, Yu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240995/
https://www.ncbi.nlm.nih.gov/pubmed/32434577
http://dx.doi.org/10.1186/s12874-020-01017-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240995/
https://www.ncbi.nlm.nih.gov/pubmed/32434577
http://dx.doi.org/10.1186/s12874-020-01017-8

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