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Optimal, minimax and admissible two-stage design for phase II oncology clinical trials
BACKGROUND: The article aims to compare the efficiency of minimax, optimal and admissible criteria in Simon’s and Fleming’s two-stage design. METHODS: Three parameter settings (p(1)-p(0) = 0.25–0.05, 0.30–0.10, 0.50–0.30) are designed to compare the maximum sample size, the critical values and the e...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240995/ https://www.ncbi.nlm.nih.gov/pubmed/32434577 http://dx.doi.org/10.1186/s12874-020-01017-8 |