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Predicting the Immunogenicity of T cell epitopes: From HIV to SARS-CoV-2

We describe a physics-based learning model for predicting the immunogenicity of Cytotoxic T Lymphocyte (CTL) epitopes derived from diverse pathogens, given a Human Leukocyte Antigen (HLA) genotype. The model was trained and tested on experimental data on the relative immunodominance of CTL epitopes...

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Detalles Bibliográficos
Autores principales:	Gao, Ang, Chen, Zhilin, Segal, Florencia Pereyra, Carrington, Mary, Streeck, Hendrik, Chakraborty, Arup K., Julg, Boris
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241102/ https://www.ncbi.nlm.nih.gov/pubmed/32511339 http://dx.doi.org/10.1101/2020.05.14.095885

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